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Introduction

Book Review: The Hungry Brain
You consider this Market incredibly impressive and powerful. The Ayurvedic actions of ginger, as described by Pole include: If sweet, heavy, oily foods are taken in too great of a quantity it can lead to greater mucous accumulation as well as further weight gain and diabetes mellitus. Antral area, fundus area and diameter, and the frequency of antral contractions were measured using ultrasound at frequent intervals over 90 min, and the gastric half-emptying time was calculated from the change in antral area. The knowledge of Ayurveda is important to the correction of all digestive imbalances.

Zinc as a nutrient for agricultural crops in southern Australia

The Zija Difference

Placentas are a defining characteristic of placental mammals , but are also found in marsupials and some non-mammals with varying levels of development. The classical plural is placentae , but the form placentas is common in modern English and probably has the wider currency at present. The placenta functions as a fetomaternal organ with two components: Placental mammals, such as humans, have a chorioallantoic placenta that forms from the chorion and allantois.

It has a dark reddish-blue or crimson color. Vessels branch out over the surface of the placenta and further divide to form a network covered by a thin layer of cells. This results in the formation of villous tree structures. On the maternal side, these villous tree structures are grouped into lobules called cotyledons.

In humans, the placenta usually has a disc shape, but size varies vastly between different mammalian species. The placenta occasionally takes a form in which it comprises several distinct parts connected by blood vessels. If there is a clearly discernible main lobe and auxiliary lobe, the latter is called a succenturiate placenta. Sometimes the blood vessels connecting the lobes get in the way of fetal presentation during labor , which is called vasa previa.

The corresponding specific proteins are mainly expressed in trophoblasts and have functions related to female pregnancy. The placenta begins to develop upon implantation of the blastocyst into the maternal endometrium. The outer layer of the blastocyst becomes the trophoblast , which forms the outer layer of the placenta. This outer layer is divided into two further layers: The syncytiotrophoblast is a multinucleated continuous cell layer that covers the surface of the placenta.

It forms as a result of differentiation and fusion of the underlying cytotrophoblast cells, a process that continues throughout placental development. The syncytiotrophoblast otherwise known as syncytium , thereby contributes to the barrier function of the placenta.

The placenta grows throughout pregnancy. Development of the maternal blood supply to the placenta is complete by the end of the first trimester of pregnancy week 14 DM. In preparation for implantation of the blastocyst, the uterine endometrium undergoes "decidualisation". Spiral arteries in decidua are remodeled so that they become less convoluted and their diameter is increased. The increased diameter and straighter flow path both act to increase maternal blood flow to the placenta.

There is relatively high pressure as the maternal blood fills intervillous space through these spiral arteries bathes the fetal villi in blood, allowing an exchange of gases to take place.

In humans and other hemochorial placentals, the maternal blood comes into direct contact with the fetal chorion , though no fluid is exchanged. As the pressure decreases between pulses , the deoxygenated blood flows back through the endometrial veins.

This begins at day 5 - day 12 [11]. Deoxygenated fetal blood passes through umbilical arteries to the placenta. At the junction of umbilical cord and placenta, the umbilical arteries branch radially to form chorionic arteries.

Chorionic arteries, in turn, branch into cotyledon arteries. In the villi, these vessels eventually branch to form an extensive arterio-capillary-venous system, bringing the fetal blood extremely close to the maternal blood; but no intermingling of fetal and maternal blood occurs "placental barrier".

Endothelin and prostanoids cause vasoconstriction in placental arteries, while nitric oxide causes vasodilation. The fetoplacental circulation is vulnerable to persistent hypoxia or intermittent hypoxia and reoxygenation, which can lead to generation of excessive free radicals. This may contribute to pre-eclampsia and other pregnancy complications.

This begins at day 17 - day 22 [15]. Placental expulsion begins as a physiological separation from the wall of the uterus. The period from just after the child is born until just after the placenta is expelled is called the "third stage of labor". Placental expulsion can be managed actively, for example by giving oxytocin via intramuscular injection followed by cord traction to assist in delivering the placenta.

Alternatively, it can be managed expectantly, allowing the placenta to be expelled without medical assistance. Blood loss and the risk of postpartum bleeding may be reduced in women offered active management of the third stage of labour, however there may be adverse effects and more research is necessary.

The habit is to cut the cord immediately after birth, but it is theorised that there is no medical reason to do this; on the contrary, it is theorized that not cutting the cord helps the baby in its adaptation to extrauterine life , especially in preterm infants.

The placenta is traditionally thought to be sterile , but recent research suggests that a resident, non-pathogenic , and diverse population of microorganisms may be present in healthy tissue. However, whether these microbes exist or are clinically important is highly controversial and is the subject of active research. The placenta intermediates the transfer of nutrients between mother and fetus.

The perfusion of the intervillous spaces of the placenta with maternal blood allows the transfer of nutrients and oxygen from the mother to the fetus and the transfer of waste products and carbon dioxide back from the fetus to the maternal blood. Nutrient transfer to the fetus can occur via both active and passive transport.

Waste products excreted from the fetus such as urea , uric acid , and creatinine are transferred to the maternal blood by diffusion across the placenta. IgG antibodies can pass through the human placenta, thereby providing protection to the fetus in utero. IgM , however, cannot cross the placenta, which is why some infections acquired during pregnancy can be hazardous for the fetus.

Furthermore, the placenta functions as a selective maternal-fetal barrier against transmission of microbes. However, insufficiency in this function may still cause mother-to-child transmission of infectious diseases. The placenta and fetus may be regarded as a foreign allograft inside the mother, and thus must evade from attack by the mother's immune system.

However, the Placental barrier is not the sole means to evade the immune system, as foreign fetal cells also persist in the maternal circulation, on the other side of the placental barrier. The placenta also provides a reservoir of blood for the fetus, delivering blood to it in case of hypotension and vice versa, comparable to a capacitor. The placenta often plays an important role in various cultures , with many societies conducting rituals regarding its disposal. In the Western world , the placenta is most often incinerated.

Some cultures bury the placenta for various reasons. The placenta is believed by some communities to have power over the lives of the baby or its parents. The Kwakiutl of British Columbia bury girls' placentas to give the girl skill in digging clams, and expose boys' placentas to ravens to encourage future prophetic visions. In Turkey , the proper disposal of the placenta and umbilical cord is believed to promote devoutness in the child later in life.

In Ukraine , Transylvania , and Japan , interaction with a disposed placenta is thought to influence the parents' future fertility. I took 1 aniracetam and 1 aplha gpc today and the feelings was absolutely unreal i felt the best i had in years im 26 years old although i felt a bit sleepy and possibly slight brain fog rather than enhanced cognition, my question is what is the best way to take these, should i stack them to get maximum benefits or take them all consecutively?

Alan, we have detailed dosage instructions for every one of these nootropics. Scroll through the list here: And click through to each review. Each review explains how the nootropic works in your brain.

The amount to use and what to take with it to make sure it works. I also suggest you only use one racetam at a time until you learn how each works. And how your body responds to it. You likely felt sleepy because your dose of Alpha GPC was too low for the amount of Aniracetam you took.

If you miss either of those it is unlikely you will experience much from using this nootropic. And it then feels like nothing is happening.

Driving north early in the morning on I was amazing. Everything was crystal clear and my reaction time moved up a couple notches. But when I miss using Aniracetam for 3 or 4 days in a row I know it. Would it be safe for me to start taking nootropics at this age? Somewhere on this site is research on brain development and age.

But it would take some searching to find it. And if you did, be very careful about what you use. But most of the serious heavy lifting is from birth to late teens. So in your case and at your stage of develop just please be careful.

That includes stuff you can get off the interweb. The racetams should be OK as long as you follow dosage instructions very carefully. And no matter what you do support your brain with the basics. That with unrefined coconut or MCT Oil can give you an edge.

Final word is use common sense. You can up your game without over-amping your brain. Always do the fundamentals no matter what you try. And use adaptogens and anything that assists nerve growth factor and BDNF. Continual brain repair and listening to your body is key.

David thank you so much for the quick reply! Charles, best way to get a better understanding of nootropics and different options for stacks is read some of the posts linked to from this page: Each post title is fairly descriptive of what the post is about. And there is a short summary there as well. I also just ordered Mind lab pro! Also, would it be worthwhile to add ashwagandha to the stack? Mostly as another adaptogen and the reaction timing and calmness its known for?

And adding one regular dose of Mind Lab Pro will increase it to 1, mg total. Ashwagandha is an acetylcholinesterase inhibitor. Which means it increases acetylcholine ACh.

Adding it to your stack will push you over the top into nasty territory more than likely. With too much acetylcholine. Mind Lab Pro benefits kick in at different times for different people. But may not notice a difference for awhile. The effects are powerful but subtle because it works on total brain optimization. And unless you are very in-tune with your body ….

I would start with one dose of MLP and see how you feel. I personally use one dose of MLP in the morning and another at noon. But my brain is very Adult ADD. And needs the help. Piracetam may give you the noticeable difference you are looking for. But please follow dosage instructions carefully. And take another look at the amount of Citicoline you are using.

And carefully evaluate each one before adding any one of them to your stack. How much citicoline would you recommend then? Perhaps mg, or just stick to the dosage of mind lab pro? I remember reading one of your articles and it saying to keep a 1: Also how can I buy your book? Charles, try mg of Citicoline and Mind Lab Pro and see how you feel. When you start with Piracetam you may need to increase your dose.

See the side effects section for CDP-Choline so you know what to watch out for. Too much acetylcholine usually feels like fatigue or getting sleepy. And judge how you feel the first day. However, looking for a bit of clarity here. I went with your recommendation of lowering the citicoline. When i started taking MLP i did so with only 1 mg cap. My initial thoughts on this were to see if it was something having to do with life circumstances on some of the days due to lack of sleep or a certain event that went on one day.

However, after 3 straight days of it I thought perhaps I was still using too much Citicoline based on the side effects in your article on CDP Choline. I then stopped taking the mg cap today and just took the MLP.

What are your thoughts? I would say increase your choline intake and see how you feel. But if I did, it would likely only feel like fatigue. But those headaches are particularly nasty. One capsule of Alpha GPC and the headache goes away. Everyone of our brains are unique in who know how many ways. It is possible your brain just needs more choline. I hope this email reaches you well. I hope you can help me?

At one party 6months ago, I took an Ecstacy pill drug which made me very very happy. At that moment, none of the above problems were visible.

I felt like my old young self, with full confidence. I researched and found out that Esctacy releases serotonin and that explains the amazing feeling. I have bought a 5 HTP supplement and each capsule has: Dee, you are on the right track. Because increases one neurotransmitter will soon throw off the balance of other in your brain.

Which is the reason why we need to be careful about balancing serotonin with dopamine. The real issue is you cannot make serotonin or dopamine without the assistance of certain vitamins and minerals. Your best option is find a high quality B-Vitamin supplement that uses all nature-identical ingredients.

In other words, folate rather than folic acid. And methylcobalamin rather than cyanocobalamin. And the doses of every vitamin you take needs to be high enough to provide a benefit. Usually much higher than the government issued RDA.

Each of these nootropics have full reviews here on Nootropics Expert. Including dosage recommendations, side effects and types to buy. Dosage recommendations must be followed for any of these including vitamins to work.

Thank you for the reply. David, I have been trying to find a B-Vitamin supplement after reading your article, all natural and high dosage per serving. I can really see how important B-Vitamins are now.

And start experimenting with some adaptogens. Try them one at a time and see how you feel. Each has a link through to the full review with dosage instructions.

There is no natural substance that will give you the effect you got from Ecstasy. But as good as it felt, it is not sustainable. Your long-term solution is a stack of supplements. But it will take time and experimenting to find the right combination for you. Can you recommend a neurologist or doctor? I struggle with the feeling of having a cloud over my brain, a really bad case of brain fog as well as low blood pressure. I also tend to procrastinate a lot.

I was taking Ritalin and Red Bull, and that helped however I am aware of how unhealthy it is. And I can visually see the premature aging effect its had on me, it looks like I aged at least five years in the last two when I started taking Ritalin and Red Bull. We do not recommend specific neurologists or doctors here. No one else can do this for you. Especially not a mainstream doctor. You must learn how to do it yourself using the information provided here on Nootropics Expert.

What are your thoughts on dmg? Would consider a youtube video as well on the subject. Thanks for the amazing content. Is it fluvoxamine a nootropic? Felipe, Lithium Carbonate is prescribed for long-term treatment of bipolar disorder, is dosed at — mg and comes with a host of side effects. Dosage is 5 mg. Hello, I have problem with focus, motivation, experiencing pleasure and mood, also some anxiety, as I think, I have low levels of dopamine, but the doctor prescribed me SSRI, as they always do, when they see symptoms of depression, without analyzing them.

I bought some stack, that contains L-dopa, L-tyrosine, Acetyle-L-Carnitine and alpha-GPC, I want to add Rhodiola rosea and CDP-choline to this stack, would it be a good choice or all of these together can cause any problems and side effects? George, sounds like you are on the right track if you think you have a dopamine issue. Unless the intention was to boost dopamine as much as you can.

See how this stack works for you for a few days first. Also, see my post on depression here for more ideas: I thought as the dopamine levels will raise, it may cause dopamine receptors down regulation and I have heard, that CDP-choline increases dopamine receptors count, so to achieve maximum result, I want to add it to the stack, but also I thought that CDP-choline together with Alpha-GPC and acetyl-L-carnitine, could be too much. Also I want to know, how long can I take such kind of nootropics, several weeks, months, or there is no limitation for them?

I would be less concerned at this stage in down-regulating dopamine receptors and more concerned about depressing serotonin. Because both are involved in anxiety and mood.

Be very careful with St. Please read this review several times until you know exactly what to expect and watch out for: George, I take them every day and it works for me. But everyone is different. It all depends on your goal. Do you want consistent improvement in cognition? Or are you looking for some dramatic reaction you can feel? Hello again, David, one more question, when should I take supplements, for maximum absorption through blood brain barrier?

George, tyrosine is an amino acid and competes for transporters to your brain with other amino acids from your food. It has nothing to do with the blood-brain barrier directly. Fat-soluble supplements need a healthy fat like coconut oil for absorption and to be able to cross through cell walls. I have multiple health issues: I have low levels of Dopamine, serotonin, and acetylcholine, possibly due to upregulations of the COMT enzyme. Last week, I tried mg Sulbutiamine for the first time. My fatigue, depression, brain fog, and low libido vanished!

These results lasted only 2 days, however, and the last several days I have felt worse than ever. Karen, some people report tolerance when using Sulbutiamine. But not after two days. You could try using it ever 2nd day and see if that works for you. And remember that Sulbutiamine is fat-soluble so you need to take it with a healthy fat like unrefined coconut oil for it to get into your cells.

You might be on to something here. Then scroll through the posts listed on this page: Start with the basics like vitamins, minerals, healthy fats, and build from there.

You will likely end up with a nootropic stack containing at least 6 supplements to get you where you want to be. And it will evolve and change as you gain more experience. If I start taking rytalin, I should take all of my life? I did fine with the stack for an entire year without Ritalin. The ADHD stack is designed to boost dopamine to consistent levels, increase acetylcholine for brain signaling, all while repairing brain cells and keeping depression down.

Use it consistently for 3 — 4 weeks and then decide how you feel. It may take awhile to repair your brain enough for it to work. Hopefully, what you find here on Nootropics Expert will give you and your family some relief.

Thanks David, I have been researching neuroscience from the period I started feeling symptoms of the depression and it helped me a lot. I try to stay away from medications and find other way, with healthy lifestyle and supplements, so I find your posts and videos very helpful.

I wrote about my pressure before. I want to make fit and strong body through work out. I knew that but I cant help it. I think I have an obsession with time management and self control.

This makes me so depressed. I want to change myself in many way. I tried a lot. I want to have a nice reputation. I think everybody change themselves in better version. I think I am fragile person when situation is really bad. I know that it could not make a dramatic change but I will do my best. I visit your blog everyday and read again and again hoping that I will find any possibility making me a better me.

Hello David, I want to ask a little bit off topic, which supplements are good to raise dopamine and serotonin levels fast and only at that moment of taking them, to feel euphoric and get music enhancement little bit close to Mdma, Lsd, or cannabis? I have read, that one guy took mg of 5htp and aslo B6 vitamins and felt very euphoric and without any comedown or hangover, so I think about something like that.

Also if you can give some advice which supplements are good to prevent Mdma Neurotoxicity and good after comedown starts, to restore depleted serotonin? Only other thing I can think of possibly providing some state of euphoria is snorting cocao: I am wondering what supplements might be beneficial for the body to repair injury or damage to peripheral nerves? Might vitamin b, benfotiamine, lions mane mushroom, magnesium, lecithin, acetyl-l-carnitine, or vitamin-d help? There is just so many.

Any guidance would be appreciated. Gregory, yes and all of the above. Also, add a high quality multivitamin to this stack. Like the one I just reviewed here: Do a search for that keyword here on Nootropics Expert and see what turns up. Thanks very much David. I am 37 so does that mean I should be skipping the ubiquinol in favour of CoQ10?

Also might Forskolin be helpful? See the difference between Ubiquinol vs Ubiquinone in this review: Some claim one works better than the other but the only real way to find out is try each one to see which is most effective for you. You could try Forskolin but Pine Bark Extract may be a better choice for you: Do you have info anywhere? Gregory, the only information I have on potassium has to do primarily with brain health: Hi how are you?

Im taking lithium carbonate, fluvoxamine and olanzapine I wold like ond nootroopic guide for students. Nootropic like better cognition, short memory and motivation Thanks. Felipe, choose one nootropic from each category on this post on Learning and Memory here: But before you try each nootropic, check to see if there are any contraindications with any of the prescription drugs you are using.

Hi David how are you, its Felipe again Can fluvoxamine and olanzapine benefits my brain? For motivation, wich nootropic you recomend? Felipe, it depends on who you ask about fluvoxamine and olanzapine about benefits to the brain and overall health.

The manufacturers would argue that they do. But for olazapine, the maker was ordered to settle literally billions in law suits. Anyone using a prescription drug should research exactly how the drug works. Including side effects associated with that drug. Motivation is related to dopamine and and how it is used in your brain. Including activation of AMPA receptors. Please study my post here on motivation: Then put together a stack of 4 — 5 nootropics from that list and see if they help your motivation levels.

Hi David, I have strange feeling, it feels like, everything is normal with, but I get bored with doing things too fast, I enjoy them for the first time, but than every time I get so bored, I lose all of the interest. The thing is that, in my childhood and even two years ago, I was totally opposite, I enjoyed things too much and for a very long time. I am against of medication, so maybe you could give me some advice and I want to try some supplements, that might help? I will be very thankful.

Put together a stack from the nootropics listed further down in that post. But include only one of the racetams at a time until you find one that works for you.

And place close attention to the dosage instructions for each of these nootropics. Detailed dosage instructions are included in each individual review. I have read your many posts and I am thinking about this stack: Nick, this sounds like a good start. Find an Omega-3 supplement that provides at least 1, mg of DHA. Make sure your B-Complex is all nature-identical. The doses are much higher than RDA.

Last bit of advice is follow dosage recommendations from each review here on Nootropics Expert. Try this for 2 or 3 weeks and report back please. I saw, that you wrote about Nalt, mg 3 times per day, it means mg per serve, in total mg, or mg diveded 3 times? Also how much L-dopa do you recommend each day, I am little bit worried, that L-dopa may cause hair loss? And final question about serotonin. One thing I have learned is to listen to my body and try to give it what it wants and needs.

Start at the low end of dosing and work from there. I am fairly new to the world of nootropica but I got pushed into it by a friend, after he heard that I take a lot of anti depressants to cure my anxiety attacks. I have inhalated a lot of your articles and wanted to thank you, for your work! Trough my readings I have stumbled across L-Theanin as a substitute for my anti depressants, because it causes alpha waves in the brain, what is associated with stressrelief if I got that right.

Do you think that it is worth a try to fully substitute my medicine with something like that? Do you maybe have a nootropica stack ready that could deal with my problems? Stevie, L-Theanine may help with your anxiety issues. And several other nootropics may help as well.

Please see this post I wrote on social anxiety which applies to any type of anxiety issues: To find the right nootropics for you, first determine what is likely causing the problem.

A good place to start is the medications you use that you find helpful. Then find out exactly how they work in your brain.

A good place for research on prescription drugs is Wikipedia. The next step is finding out what nootropics work in a similar manner. But a BIG note of caution here … Some of these nootropic supplements are extremely powerful. Because you could cause Serotonin Syndrome or a hypertensive crisis depending on the neurotransmitters involved. I am really impressed on how much time you take to answer every question.

So first of all: I am going to read your suggestion and try to find what I need to substitute. If I need help, I hope that I can ask you again. I will take all the steps you mentioned and I hope I can find a way to substitute that. The big difference is Lithium Orotate is dosed 5 mg while Lithium Carbonate is dosed — 1, mg.

And comes with side effects. Hi David, thank you for all the helpful information you provide. Im currently on Lexapro for depression, but I also suffer from anxiety, especially social anxiety.

Im going to a sales job and was wondering what might be a decent nootropic stack for me. Im already taking aniracetam, Sulbutiamine, and Mind Lab Pro.

So two questions, should I change or add to these? Also, should any of them be cycled and how often? Thank you in advance. Some say you should cycle the first two but that has not been my experience. Please see this post: I would add DHA and magnesium to your stack to start with, along with a high quality, high-potency B-Complex supplement.

Then choose a couple of nootropics from the second list on that page to try. Knowing my symptoms discussed with my counselor line up as classic ADD, I decided to try the more natural approach and treat the ADD which seems to be causing the anxiety.

I use a combination of essential oils which does wonders Vetiver, peppermint and cedarwood and eating healthy vegetarian diet and exercise are very helpful. Should I take one or the other? If so, what dosage of this? That seems like an opposite effect. For L-theanine , is the supplement best to take or just have it in green tea or matcha? How much should I drink a day? I feel that would counter act the calming aspect for good sleep?

If so, how much is recommended for each? I have B 12 but someone said other Bs are important to go with that. Lastly Fish oil — someone recommended Krill? Is that the best or does it matter which fish oil? Assuming this is good for ADD? Would you be able to help sort this out with me or recommend how I can find these answers.

Jenna, the best protocol for treating ADD with nootropic supplements is here: Just today they put him on Seroquelmg during the day and mg at night for anxiety. Do you think the MindLab nootropic would work for him or would there be something else he would benefit from?

When he starts to get anxious his face gets red and sometimes it turns into a rash like hives. Thank you in advance for your help. Betti, some clinical studies have shown that Mucuna Pruriens to be a safer option than levadopa.

Please see my review of Mucuna here: Mind Lab Pro may be able to help some but when dealing with disease that is so advanced the only way to tell is to try it. Several nootropic supplements have been shown to work for taming anxiety.

But a strong word of caution here …. Do your research before trying anything that may be contraindicated with the meds your husband is using. Some are downright dangerous and could be life threatening.

A good site to check for drug interactions is here: For example, Seroquel affects nearly ALL the major neurotransmitters in your brain. So if it boosts serotonin and you use something like St. Which can be deadly. Hello David Congratulations and thanks; this is a very informative web site that you have. I dont feel any benefit from this treatment-adiction régimen, just: Afther all these years i thing it seems evidently that there is a deterioration in my brain capacities, in my synaptic conections, neurons, or neurotransmiters and of course becouse of that: I want something that help with this brain condition and i need NOT to take any more this SSRI Sertraline , but how to do it without have a bad time with the withdrawl effects in my brain?

What are my options? I been reading that 5htp triptofan or St. Johns Worth are two of the most popular natural remedies for SSRI substitution, or eficcient alternatives for the withdrawl situation. Do i have precisely to take one of those? Or maybe better some nootropic stuff aminoacid, herbs, adaptogens, syntetic nootropics, vitamins or minerals, etc.

For example David, im planing to use the following suplements like posible tools and im not saying that i will take it all those regularly or a the same time in a stack, but some of theme maybe yes. Can you tell me David, Wich of these ones do you believe i need to put out of the list? What else i will need preferently that im not consider here? In advance thanks for your answer David. But to make this work you need to follow dosage recommendations for each.

I am not a doctor and do not even play one on TV! Including 5-HTP and St. David, I have a serious question. My boyfriend is 24, and he has a very strange kind of panic attack. It breaks my heart to see him like this. He had a very traumatic childhood, as well. Which would you recommend to calm him, maybe raise pain relieving endorphins?

Anything, from ones that can act very fast in the moment to calm him and relax his muscles or ones that work on a longer basis. Money is incredibly tight right now and I need something fast. Which do you think would be most likely to work? Your site is amazing. Mari, try Lithium Orotate: You may need to use 2 tablets at a time. I have a small benign tumor on my right side of the brain the lobule that is near de ear; can you comment about nootropics for it.

Thank you for the attention you can give to this message and your generosity on sharing. Nilsa, Curcumin is one of the most potent natural anti-tumor remedies available: Just make sure you choose the right supplement that includes BioPerine to improve bioavailability and you dose it high enough. Hello David, First of all I want to thank you for making this tremendous resource of information available.

I am on day two of taking Luminol and have Mind Lab Pro on its way to me in the mail. The initial results from Luminol are quite impressive. I have noticed my impulsivity is gone and my focus and sense of purpose is greatly sharpened.

My main question for you is I am wishing to know if there is a danger to take the Mind Lab Pro along with the Luminol, due to the combination of different stacks.

Is there a safe way to do this, or would it be best to either only take one or the other. I was planning IF I take both, to space it out, so a few hours pas between taking one and then the other. I would greatly value your advice. David, I need more information about Luminol before I can comment.

What is it and what it its mechanism of action in the brain? Luminol has Noopept as the chief ingredient. Best thing to do is look up each individual supplement here on Nootropics Expert and check dosages for each. Then look at the dosages for each pre-formulated stack and make sure they are within the safety range. Two months ago I came across the PEA selegiline combo.

In contrast to what you said, however, I did build a tolerance. My starting dose was 1 gram and I already needed to take more the following day to achieve the same effect. And the comedown became worse and worse. After about 2 weeks I was taking over 3 grams every hours, so I decided to stop.

But now after watching your video, I asked myself, did I actually have real PEA or was it not correctly synthesized?! Can you tell me a source that sells real PEA? Both claim to test their product before sale. You could ask for a Certificate of Analysis for the batch you intend to buy. Next best thing is read through the reviews and see what others are saying. The thing about using such large amounts of any nootropic and tolerance is you damage receptors and synapses.

I suggest you look for ways to do some neuron repair. And take a look for other ideas in this post on traumatic brain injury because the ideas apply: Just want to be able mentally to have the motivation to work out and also would love to boost my brain.

Your email address will not be published. This site uses Akismet to reduce spam. Learn how your comment data is processed. The Definitive Guide to Nootropics A nootropic is a substance that enhances cognition and memory and facilitates learning.

The Big List of Nootropics Nootropics cover a broad category of compounds with cognitive boosting properties. They have minimal side-effects and are appropriate for long-term use. The Best Nootropics Achieving brain optimization comes with a lot of trial and error. Wondering Where to Start? There's a Nootropic For That Get "Secrets of the Optimized Brain," pages to help you plan your Nootropic Stack when you sign up for updates: Comments Have you heard of sluggish cognitive tempo?

And let me know if you have any questions. Hi David, I am learning so much from your site. I just ordered Phenibut and LTheanine, but also drink lots of green trea. Hi David, Me again: Also have an issue with adrenals so use adrenal cortex 4-times per day. Thank you for all the great info, David! Thyroid Probs are wicked! Mirna You can send your blood test results to life extension magazine ànd put on the envelope lab review and one of their specialists will go over your blood work with you.

Hi David, In searching the internet for information on Nootropics, your website really stands out. Hi David This is a great site, and filled with valuable information.

Thanks again for the absolutely great website. I have 4 questions. Why are you so generous with your time and knowledge? Here are a couple of posts that may help planning your stack for the future: Also considering adding NADH 5mg and extra zinc 15mg and copper 1mg to the mix.

Any guidance or warnings regarding this stack would be greatly appreciated. Thanks again for your input. Hello David, I would like to ask your opinion on the product Qualia.

Thanks for your very informative video on velvet bean. Thanks again for your prompt response to my previous query. Below is a brief summary of my medicated world of mental health: All the best, M.

Phenibut the night before may have some influence. But I have no proof that it does. That being said, at first glance, what would you recommend as an intro into this area?

The Definitive Guide to Nootropics